Kinase/Phosphatase Drug Discovery & Development

Kinases/Phosphatases as Therapeutic Targets

Disruption of kinase/phosphatase balance may directly cause or to be a consequence of many pathological conditions, making them potential and important targets for the development of therapeutic drugs. Creative BioMart has established a plethora of assays and continues to develop new approaches to support integrated kinase/phosphatase drug discovery programs, starting with initial steps of target identification and validation.

Drug design plays a crucial role in the drug discovery process. Evolving techniques and strategies will shed new light on the future directions of kinase/phosphatase drug design for future targeted therapeutics. Creative BioMart offers expertise and state-of-the-art technology platforms to help our customers overcome challenges in designing drugs targeting phosphorylation pathways.

Kinases/Phosphatases Drug Design

Discovery of Therapeutic Kinase Inhibitors

Since the first kinase inhibitor, imatinib, was approved in 2001, the number of approved kinase inhibitors has increased each year. However, there are still a large number of kinases that have not been well studied, suggesting that the field of kinase inhibitor discovery remains immature. Creative BioMart aims to provide our customers with integrated solutions to accelerate their drug discovery process for kinase inhibitors.

Unlike kinases that have been successfully developed as targets for several approved drugs, phosphatases have long been considered “undruggable”. Creative BioMart has a team of scientists with diverse disciplinary backgrounds and extensive experience in developing phosphatase-directed therapeutics who are fully committed to helping our customers make the undruggable phosphatases druggable.

Discovery of Therapeutic Phosphatase Activators and Inhibitors

Kinase/Phosphatase-Targeted Antibody Drug Discovery

Advances in kinase/phosphatase biology have led to an explosion in the number of antibody drug pipelines. Creative BioMart has unparalleled expertise and innovation to provide our customers with integrated kinase/phosphatase-targeted antibody drug discovery solutions from genes to therapeutic antibody candidates. Our highly skilled scientists strive to use reliable data to guide our customers throughout the whole process.

With many years of experience in drug development, Creative BioMart is committed to providing our customers with integrated solutions that are completely customer tailored for the preclinical development of kinase and phosphatase drugs, from safety and efficacy evaluation to formulation. We deliver high-quality data in a fast turnaround time to help our customers initiate the clinical drug development process as soon as possible.

Preclinical Development of Kinase/Phosphatase Drugs